{"product_id":"larimedical-comedopeel-serum-15ml","title":"Comedopeel Serum 15ml","description":"\u003cp\u003eProduct specifically designed to incorporate the exact amount of moisturizers after peeling. It provides different natural raw materials that help keep the dermis free of comedones, preventing excessive cell proliferation. It also provides the necessary sun protection after a peel to avoid irritations and inflammatory reactions.\u003c\/p\u003e\u003ch4\u003eKey ingredients\u003c\/h4\u003e\u003cul\u003e\n\u003cli\u003eSalicylic Acid\u003c\/li\u003e\n\u003cli\u003ePlantago Lanceolata Leaf Extract\u003c\/li\u003e\n\u003cli\u003eBerberis Aquifolium Extract\u003c\/li\u003e\n\u003c\/ul\u003e\u003cp\u003e\u003cstrong\u003e96% skin-friendly ingredients of natural origin:\u003c\/strong\u003e Alcohol, Propylene Glycol, Plantago Lanceolata Extract, Berry Extract, Avocado Oil, Salicylic Acid\u003c\/p\u003e\u003ch4\u003eHow to use\u003c\/h4\u003e\u003col\u003e\n\u003cli\u003eClean and prepare the area to be treated.\u003c\/li\u003e\n\u003cli\u003eApply Comedopeel Serum in the morning and at night after a treatment with Comedopeel or Comedopeel Plus in the cabin.\u003c\/li\u003e\n\u003cli\u003eLet dry.\u003c\/li\u003e\n\u003c\/ol\u003e\u003ch4\u003eInflammatory Comedogenic Acne\u003c\/h4\u003e\u003cp\u003eDespite extensive research over the past century, the pathogenesis of acne vulgaris remains unclear. In particular, the sequences of events that are involved in comedogenesis have yet to be clarified. Comedogenesis is one of the four main etiological factors of acne; the others are increased production and secretion of sebum, colonization of the follicular ducts with Propionibacterium acnes (P. acnes), and the inflammatory response. These four factors should not be viewed as different phases, but rather as closely interrelated mechanisms that ultimately lead to the clinical disease of acne vulgaris.\u003c\/p\u003e\u003cp\u003eThat comedones are essential lesions in acne was first suggested in 1960. It is widely accepted that their pathogenesis is multifactorial, attributable to follicular hyperkeratinization, increased sebum production, increased androgenic activity, impaired quality of sebum lipids, dysregulation of cutaneous steroidogenesis, neuropeptide production, inflammation and follicular hypercolonization by P. acnes bacteria.\u003c\/p\u003e\u003cp\u003eOne of the most widely used mechanisms to stop the hyperkeratinization process consists of the physical or chemical elimination of the excess proliferation of keratinocytes in the deregulated stratum and thus prevent the obstruction of the pilosebaceous duct.\u003c\/p\u003e","brand":"Larimedical","offers":[{"title":"Default Title","offer_id":49153549664478,"sku":"LMED014","price":110.0,"currency_code":"AUD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0644\/1363\/0686\/files\/LARIMEDICAL_COMEDOPEEL_SERUM.jpg?v=1791260194","url":"https:\/\/zwarbeauty.com.au\/products\/larimedical-comedopeel-serum-15ml","provider":"zwarbeauty","version":"1.0","type":"link"}